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Chronic pain: the search for a killer

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Researchersí discovery of why sunburn hurts reveals possible target for new pain relief drugs

New award funding of LPC

UK researchers tackle pain

Imperial College and the London Pain Consortium partner with a Japanese chemical company to fight chronic pain

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Walking on Fire click here

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London Pain Consortium: key Discoveries

Reserachers: Pain killers click here

Painstaking research - tackling chronic pain click here

The London Pain Consortium making a difference
Wellcome Trust conference The Challenges of Chronic Pain

11-13 March 2015
Wellcome Trust Genome Campus, Hinxton, Cambridge, UK

Abstract deadline: 30 January 2015
Registration deadline: 16 February 2015

For more information
click here

Archive workshop and seminar slides Professor Peter Karmerman…
 
Ph.D. Positions
Why do a PhD in pain research?
In the past two decades pain has become one of the most exciting fields of nervous system research. Pain is required for maintaining the integrity and survival of the organism but sustained or chronic pain can result in secondary symptoms such as anxiety and depression and can dramatically decrease quality of life. CNS areas that are activated by pain-producing stimuli show remarkable plasticity. Noxious stimulation always results in changes in gene expression within the central nervous system and different chronic pain states generate unique neurochemical and pharmacological signatures in the brain. New insights into how sensory information is centrally processed in the face of a constantly changing molecular architecture will fundamentally change the way we approach pain control and develop new analgesics. Pain is also a model system for many fundamental questions in neurobiology, such as specification of cellular phenotype, formation of appropriate connections, maintenance of stability in normal function, mechanisms underlying plasticity, and the processes leading to disintegration of normal function during aging and disease.
The recent rapid progress in pain research has been driven by molecular and cell biology. These techniques continue to identify genes potentially important in pain processing, and have stimulated the search for novel analgesic drugs as well as promoting understanding of a number of general neurobiological phenomena, such as activity-dependent plasticity. Yet the function of these genes often remains poorly understood, even though there is now a wide range of transgenic mice which allow examination of particular gene function in the whole animals. The challenge for the future is to combine cellular and molecular advances with physiological and pharmacological techniques to understand the integrated functioning of the nervous system related to the clinical problem of pain.