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Notice Board Topics
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| NK-1 receptors and developing pain pathways |
| The aims of this project are to (i) characterize postnatal expression of NK-1 receptors in the dorsal horn of young and adult rats. (ii) investigate whether lamina I NK-1 expressing neurons and the parabrachial nuclei can be activated by noxious stimuli in the postnatal rat (iii) to investigate whether NK-1 has a role in mediating responses to acute and chronic responses to noxious stimuli in postnatal animals (iv) to assess the long term effects of ablation of dorsal horn NK-1 receptor expressing cells on the developing pain system. |
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