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Notice Board Topics
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Seminar Series 2013 LPC Seminar, Tuesday 11th June 2013
Venue: King’s College London
Host: Professor Steve McMahon
Speaker: Professor Marco Martina, Department of Physiology, NorthWestern University, Chicago
Link: http://physio.northwestern.edu/faculty/marco-martina/
Schedule of events:
* 11:00-12:00pm - Workshop – ‘Role of individual ion channels in neuronal function: potential clinical impact’
- Large meeting room, Wolfson Centre for Age-related Diseases, Guy’s Campus, King’s College London
* 12:30-1:30pm - Lecture – ‘Painful memory: the limbic system in neuropathic pain’
- Large meeting room, Wolfson Centre for Age-related Diseases, Guy’s Campus, King’s College London
Location:
Click here for location map
Click here for campus map
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| 2004 |
Wood JN, Abrahamsen B, Baker MD, Boorman JD, Donier E, Drew LJ, Nassar MA, Okuse K, Seereeram A, Stirling CL, Zhao J. Ion channel activities implicated in pathological pain. Novartis Found Symp. 2004;261:32-40; discussion 40-54
Slack SE, Pezet S, McMahon SB, Thompson SW, Malcangio M. Brain-derived neurotrophic factor induces NMDA receptor subunit one phosphorylation via ERK and PKC in the rat spinal cord. Eur J Neurosci. 2004 Oct;20(7):1769-78
Nassar MA, Stirling LC, Forlani G, Baker MD, Matthews EA, Dickenson AH, Wood JN. Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain. Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12706-11. Epub 2004 Aug 16
Matthews EA, Dickenson AH. Effects of spinally administered adenine on dorsal horn neuronal responses in a rat model of inflammation. Neurosci Lett. 2004 Feb 19;356(3):211-4
Poon WY, Malik-Hall M, Wood JN,, Okuse K. Identification of binding domains in the sodium channel Na(V)1.8 intracellular N-terminal region and annexin II light chain p11. FEBS Lett. 2004 Jan 30;558(1-3):114-8 |
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| 2003 |
Selected Principle Investigators publications
Urch CE, Donovan-Rodriguez T, Dickenson AH. Alterations in dorsal horn neurones in a rat model of cancer-induced bone pain. Pain. 2003 Dec;106(3):347-56
Ramer MS, Bradbury EJ, Michael GJ, Lever IJ, McMahon SB. Glial cell line-derived neurotrophic factor increases calcitonin gene-related peptide immunoreactivity in sensory and motoneurons in vivo. Eur J Neurosci. 2003 Nov;18(10):2713-21
Rogelj B, Hartmann CE, Yeo CH, Hunt SP, Giese KP. Contextual fear conditioning regulates the expression of brain-specific small nucleolar RNAs in hippocampus. Eur J Neurosci. 2003 Dec;18(11):3089-96
Farquhar-Smith WP, Rice AS. A novel neuroimmune mechanism in cannabinoid-mediated attenuation of nerve growth factor-induced hyperalgesia. Anesthesiology. 2003 Dec;99(6):1391-401
Suzuki R, Green GM, Millan MJ, Dickenson AH. Electrophysiologic characterization of the antinociceptive actions of S18616, a novel and potent alpha 2-adrenoceptor agonist, after acute and persistent pain states. J Pain. 2002 Jun;3(3):234-43
Suzuki R, Hunt SP, Dickenson AH. The coding of noxious mechanical and thermal stimuli of deep dorsal horn neurones is attenuated in NK1 knockout mice.
Neuropharmacology. 2003 Dec;45(8):1093-100
Urch CE, Dickenson AH. Neuronal nitric oxide synthase modulation of dorsal horn neuronal responses in the rat: a developmental study. Dev Neurosci. 2003 Sep-Oct;25(5):301-7
Carpenter KJ, Sen S, Matthews EA, Flatters SL, Wozniak KM, Slusher BS, Dickenson AH. Effects of GCP-II inhibition on responses of dorsal horn neurones after inflammation and neuropathy: an electrophysiological study in the rat. Neuropeptides. 2003 Oct;37(5):298-306
Lever IJ, Pezet S, McMahon SB, Malcangio M. The signaling components of sensory fiber transmission involved in the activation of ERK MAP kinase in the mouse dorsal horn. Mol Cell Neurosci. 2003 Oct;24(2):259-70
Walker SM, Meredith-Middleton J, Cooke-Yarborough C, Fitzgerald M. Neonatal inflammation and primary afferent terminal plasticity in the rat dorsal horn. Pain. 2003 Sep;105(1-2):185-95
Gadd CA, Murtra P, De Felipe C, Hunt SP. Neurokinin-1 receptor-expressing neurons in the amygdala modulate morphine reward and anxiety behaviors in the mouse.
J Neurosci. 2003 Sep 10;23(23):8271-80
Flatters SJ, Fox AJ, Dickenson AH. Spinal interleukin-6 (IL-6) inhibits nociceptive transmission following neuropathy. Brain Res. 2003 Sep 12;984(1-2):54-62
Urch CE, Dickenson AH. In vivo single unit extracellular recordings from spinal cord neurones of rats. Brain Res Brain Res Protoc. 2003 Aug;12(1):26-34
Passmore GM, Selyanko AA, Mistry M, Al-Qatari M, Marsh SJ, Matthews EA, Dickenson AH, Brown TA, Burbidge SA, Main M, Brown DA. KCNQ/M currents in sensory neurons: significance for pain therapy. J Neurosci. 2003 Aug 6;23(18):7227-36
Bridges D, Rice AS, Egertova M, Elphick MR, Winter J, Michael GJ. Localisation of cannabinoid receptor 1 in rat dorsal root ganglion using in situ hybridisation and immunohistochemistry. Neuroscience. 2003;119(3):803-12
Torsney C, Fitzgerald M. Spinal dorsal horn cell receptive field size is increased in adult rats following neonatal hindpaw skin injury. J Physiol. 2003 Jul 1;550(Pt 1):255-61. Epub 2003 May 23
Baccei ML, Bardoni R, Fitzgerald M. Development of nociceptive synaptic inputs to the neonatal rat dorsal horn: glutamate release by capsaicin and menthol. J Physiol. 2003 May 15;549(Pt 1):231-42. Epub 2003 Apr 4
Rudhard Y, Kneussel M, Nassar MA, Rast GF, Annala AJ, Chen PE, Tigaret CM, Dean I, Roes J, Gibb AJ, Hunt SP, Schoepfer R.Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling. J Neurosci. 2003 Mar 15;23(6):2323-32
Baker MD, Chandra SY, Ding Y, Waxman SG, Wood JN. GTP-induced tetrodotoxin-resistant Na+ current regulates excitability in mouse and rat small diameter sensory neurones. J Physiol. 2003 Apr 15;548(Pt 2):373-82. Epub 2003 Mar 21
Battaglia AA, Sehayek K, Grist J, McMahon SB, Gavazzi I. EphB receptors and ephrin-B ligands regulate spinal sensory connectivity and modulate pain processing. Nat Neurosci. 2003 Apr;6(4):339-40
Flatters SJ, Fox AJ, Dickenson AH. In vivo and in vitro effects of peripheral galanin on nociceptive transmission in naive and neuropathic states. Neuroscience. 2003;116(4):1005-12
Malik-Hall M, Poon WY, Baker MD, Wood JN, Okuse K. Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Brain Res Mol Brain Res. 2003 Feb 20;110(2):298-304
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| 2002 |
Selected Principle investigators publications
Andrews KA, Desai D, Dhillon HK, Wilcox DT, Fitzgerald M . Abdominal sensitivity in the first year of life: comparison of infants with and without prenatally-diagnosed unilaternal hydronephrosis. Pain. 2002 100:35-46
Andrews K, Fitzgerald M . Wound sensitivity as a measure of analgesic effects following surgery in human neonates and infants. Pain. 2002 99:185-192
Beggs S, Torsney C, Drew L, Fitzgerald M . The postnatal reorganization of primary afferent input and dorsal horn cell receptive fields in the rat spinal cord is an activity-dependent process. European Journal of Neuroscience. 2002 16:1249-1258
Buchan D, Shepherd A, Lee D, Bray J, Pearl F, Thornton J, Orengo C .Gene3D:Structural assignments for whole genes and genomes using the CATH domain structure database. Genome Research. 2002 Vol 12,503-514
Bradbury EJ, Moon LDF, Popat RJ, King VR, Bennett GS, Patel PN, Fawcett JW, McMahon SB . Chondroitinase ABC promotes axon regeneration and functional recovery following spinal cord injury. Nature. 2002 416:636-640
Duggan MJ, Quinn CP, Chaddock JA, Purkiss JR, Alexander FCG, Doward S, Fooks SJ, Friis LM, Hall YJ, Kirby ER, Leeds N, Mouldsdale HJ, Dickenson AH, Mark Green G, Rahman W, Suzuki R, Shone CC, Foster KA. Inhibition of release of neurotransmitters from rat dorsal root ganglia by a novel conjugate of a Clostridium botulinum toxin A endopeptidase fragment and Erythrina cristagalli lectin. Journal of Biological Chemistry. 2002 277:34846-34852
Farquhar-Smith WP, Jaggar SI, Rice ASC . Attenuation of nerve growth factor-induced visceral hyperalgesia via cannabinoid CB1 and CB2 -like receptors. Pain. 2002 97:11-21
Flatters S, Fox A, Dickenson AH . Nerve injury induces plasticity that results in spinal inhibitory effects of galanin. Pain. 2002 98:249-258
Malik-Hall M, Wood JN, Okuse K. Voltage-gated sodium channels. Receptor and Ion-Channel Trafficking, edited by S. Moss and J. Henley, Oxford University Press, Oxford, UK 2002 3-26
Mantyh PW, Clohisy DR, Koltzenburg M, Hunt SP . Molecular mechanisms of cancer pain. Nature Reviews Cancer. 2002 2:201-209
Matthews EA, Dickenson AH . A combination of gadapentin and morphine mediates enhanced inhibitory effects on dorsal horn neuronal responses in a rat model of neuropathy. Anesthesiology. 2002 96:633-640.
McMahon SB . Neuropathic pain mechanisms. Proceedings of the 10th World Congress on Pain. An Updated review: Refresher Course Syllabus, edited by Maria Adele Giamberardino, IASP Press, San Diego 2002 155-163
Nagano N, Orengo CA, Thornton JM. One fold with many functions - the evolutionary relationships between TIM barrel families based on their sequences, structures and functions. Journal of Molecular Biology. 2002 321:741-765
Okuse K, Malik-Hall M, Baker MD, Poon W-YL, Kong H, Chao MV, Wood JN . The annexin II light chain p11 regulates the functional expression of the sensory neuron specific sodium channel. Nature. 2002 417:(6889) 653-656
O'Reilly BA, Kosaka AH, Knight GF, Chang TK, Ford AP, Rymer JM, Popert R, Burnstock G, McMahon SB . P2X receptors and their role in female idiopathic detrusor instability. Journal of Urology. 2002 167(1):157-164
Pearl FM, Lee D, Bray JE, Buchan DW, Shepherd AJ, Orengo CA . The CATH extended protein-family database: providing structural annotations for genome sequences. Protein Sci. 2002 Feb;11(2):233-44
Pezet S, Malcangio M, Lever IJ, Perkinton MS, Thompson SWN, Williams RJ, McMahon SB. Noxious stimulation induces Trk receptor and down-stream ERK phosphorylation in the spinal dorsal horn. Molecular and Cellular Neuroscience. 2002 21:684-695
Pezet S, Malcangio M, McMahon SB . BDNF: A neuromodulator in nociceptive pathways?. Brain Research Reviews. 2002 40:240-249
Ramer MS, Bishop T, Dockery P, Mobarak MS, O?Leary D, Fraher JP, Priestley JV, McMahon SB (2002) Neurotrophin-3-mediated regeneration and recovery of proprioception following dorsal rhizotomy. Molecular Cellular Neuroscience. 2002 19(2):239-249
Rice ASC, Farquhar-Smith WP, Nagy I. Endocannabinoids and Pain: Spinal and Peripheral Analgesia in Inflammation and Neuropathy. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2002 66(2-3):243-256
Shepherd AJ, Martin NJ, Johnson RGShepherd AJ, Martin NJ, Johnson RG, Kellam P, Orengo CA . PFDB: a generic protein family database integrating the CATH domain structure database with sequence based protein family resources. Bioinformatics. 2002 Dec;18(12):1666-72
Suzuki R, Dickenson AH . Nerve injury-induced changes in opioid modulation of wide dynamic range dorsal column nuclei neurons. Neuroscience. 2002 111:215-228
Dickenson AH , Suzuki R, Matthews EA, Neurobiology of neuropathic pain: mode of action of anticonvulsants. European Journal of Pain. 2002 6:51-60
Suzuki R, Morcuende S, Webber M, Hunt SP, Dickenson AH . Superficial NK1-expressing neurons control spinal excitability through activation of descending pathways. Nature Neuroscience. 2002 5:1319-26
Todd AE, Orengo CA, Thornton JM. Plasticity of enzyme active sites. TIBS. 2002 27(8):419-426
Todd AE, Orengo CA, Thornton JM. Sequence and structural differences between enzyme and non enzyme homologues. Structure. 2002 10:1-20
Torsney C, Fitzgerald M . Age-dependent effects of peripheral inflammation upon the electrophysiological properties of neonatal rat dorsal horn neurons: developmental of hyperalgesia and allodynia. Journal of Neurophysiology. 2002 87:1311-7
Yiangou Y, Facer P, Sinicropi D, Boucher TJ, Bennett DLH, McMahon SB, Anand P. Molecular forms of NGF in human and rat neuropathic tissues: decreased NGF precursor-like immunoreactivity in human diabetic skin. Journal of the Peripheral Nervous System. 2002 7(3):190-197 |
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